WEE1 kinase inhibitor MK-1775 sensitizes oral tongue squamous cell carcinoma cells to radiation irrespective of TP53 status.
第一作者:
Aisha Hussein,Al-Jamaei
第一单位:
Department of Oral and Maxillofacial Surgery and Oral Pathology, Amsterdam UMC-location VUmc/Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands.
作者:
主题词
人类(Humans);嘧啶类(Pyrimidines);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞周期蛋白质类(Cell Cycle Proteins);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);核蛋白质类(Nuclear Proteins);细胞系, 肿瘤(Cell Line, Tumor);舌肿瘤(Tongue Neoplasms);抗肿瘤药(Antineoplastic Agents);头颈部肿瘤(Head and Neck Neoplasms);细胞凋亡(Apoptosis)
DOI
10.1111/odi.14269
PMID
35672254
发布时间
2023-10-02
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Oral diseases
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