首页> Cell reports> CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X.

CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X.

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第一作者： Jee-Yeon,Hwang

第一单位： Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Electronic address: jeeyeonhwang@creighton.edu.

作者： Jee-Yeon,Hwang ^[1] ; Hannah R,Monday ^[2] ; Jingqi,Yan ^[3] ; Andrea,Gompers ^[4] ; Adina R,Buxbaum ^[5] ; Kirsty J,Sawicka ^[2] ; Robert H,Singer ^[5] ; Pablo E,Castillo ^[6] ; R Suzanne,Zukin ^[7]

作者单位： Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA. Electronic address: jeeyeonhwang@creighton.edu. ^[1] Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA. ^[2] Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA; Center for Gene Regulation in Health and Disease, Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, OH 44115, USA. ^[3] Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA; Center for Immunology and Infectious Diseases, University of California, Davis, Davis, CA 95616, USA. ^[4] Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Structural & Cell Biology, Albert Einstein College of Medicine, New York, NY 10461, USA; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA. ^[5] Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, New York, NY 10461, USA. ^[6] Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA. Electronic address: suzanne.zukin@einsteinmed.org. ^[7]

关键词 AMPA receptors CP: Neuroscience dendrites mRNA localization single-molecule FISH transcription transcription sites