Systematic Investigations on the Metabolic and Transcriptomic Regulation of Lactate in the Human Colon Epithelial Cells.

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作者： Chongyang,Huang ^[1] ; Huanzhou,Xu ^[2] ; Xin,Zhou ^[3] ; Maili,Liu ^[3] ; Jing,Li ^[4] ; Chaoyang,Liu ^[3]

作者单位： State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China. ^[1] Department of Pediatrics, Division of Infectious Diseases, University of Florida College of Medicine, Gainesville, FL 32608, USA. ^[2] State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China.;University of Chinese Academy of Sciences, Beijing 100049, China.;Optics Valley Laboratory, Wuhan 430074, China. ^[3] University of Chinese Academy of Sciences, Beijing 100049, China.;Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, China. ^[4]

关键词 NMR-based metabolomics lactate mitochondrial dysfunction one-carbon metabolism polyol pathway transcriptomics

主题词 Caco-2细胞(Caco-2 Cells);结肠(Colon);上皮细胞(Epithelial Cells);人类(Humans);乳酸(Lactic Acid)

DOI 10.3390/ijms23116262

PMID 35682941

发布时间 2024-08-29

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