Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation.

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第一作者： Qingxia,Zuo

第一单位： School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.

作者： Qingxia,Zuo ^[1] ; Wanqing,Xu ^[1] ; Yanbin,Wan ^[1] ; Dongyan,Feng ^[1] ; Changsheng,He ^[1] ; Cailing,Lin ^[1] ; Dongchao,Huang ^[1] ; Feng,Chen ^[1] ; Liya,Han ^[1] ; Qi,Sun ^[1] ; Dong,Chen ^[2] ; Hongli,Du ^[1] ; Lizhen,Huang ^[3]

作者单位： School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China. ^[1] Fangrui Institute of Innovative Drugs, South China University of Technology, Guangzhou 510006, China. ^[2] School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China. Electronic address: huanglzh@scut.edu.cn. ^[3]

关键词 CRISPR/Cas9 CYP3A4 Differentiation HepaRG Knock-in

主题词细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);基因敲入技术(Gene Knock-In Techniques);萤光素酶类(Luciferases)

DOI 10.1016/j.biopha.2022.113243

PMID 35687910

发布时间 2022-06-22

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2022年152卷

113243页

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Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

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Efficient generation of a CYP3A4-T2A-luciferase knock-in HepaRG subclone and its optimized differentiation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相似文献

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相关期刊

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