Antimitotic and toxicogenetic action of Stevia urticifolia aerial parts on proliferating vegetal and mammalian cells: in vitro and in vivo traditional and replacement methods.

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作者： Paulo Michel Pinheiro,Ferreira ^[1] ; Ian Jhemes Oliveira,Sousa ^[2] ; Kamilla Nunes,Machado ^[3] ; Leonel Antônio,da Silva Neto ^[1] ; Milena Monteiro,de Freitas ^[2] ; Ingredy Lopes,Dos Santos ^[4] ; Débora Caroline,do Nascimento Rodrigues ^[4] ; Rayran Walter Ramos,de Sousa ^[1] ; Antonielly Campinho,Dos Reis ^[1] ; Maria Luisa Lima Barreto,do Nascimento ^[2] ; Ag-Anne Pereira Melo,de Menezes ^[1] ; Andréa Mendes,do Nascimento ^[3] ; José Roberto,de Oliveira Ferreira ^[1] ; Ana Paula,Peron ^[3] ; João Marcelo,de Castro E Sousa ^[3]

作者单位： Laboratory of Experimental Cancerology (LabCancer), Department of Biophysics and Physiology, Federal University of Piauí, Teresina, Brazil. ^[1] Postgraduate Program in Pharmacology, Federal University of Piauí, Teresina, Brazil. ^[2] Postgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Teresina, Brazil. ^[3] Department of Chemistry, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto, Brazil. ^[4] Laboratory of Toxicological Genetics (LapGenic), Department of Biochemistry and Pharmacology, Federal University of Piauí, Teresina, Brazil. ^[5] Center for Integrative Sciences, State University of Health Sciences of Alagoas Maceió, Brazil. ^[6] Department of Biodiversity and Nature Conservation, Federal Technological University of Paraná, Campo Mourão, Brazil. ^[7]

关键词 Allium cepa chemoprevention genotoxicity in vivo toxicity sarcoma 180