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Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women.

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第一作者: Thomas E,Bartlett
第一单位: Department of Statistical Science, University College London, London, WC1E 7HB, UK.
作者单位: Department of Statistical Science, University College London, London, WC1E 7HB, UK. [1] Department of Women's Cancer, UCL EGA Institute for Women's Health, University College London, 74 Huntley Street, London, WC1E 6AU, UK. [2] Department of Women's Cancer, UCL EGA Institute for Women's Health, University College London, 74 Huntley Street, London, WC1E 6AU, UK.;European Translational Oncology Prevention and Screening (EUTOPS) Institute, Universität Innsbruck, 6060, Hall in Tirol, Austria.;Research Institute for Biomedical Aging Research, Universität Innsbruck, 6020, Innsbruck, Austria. [3] Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. [4] Centre for Tumour Biology Department, Barts Cancer Institute, Queen Mary University of London, London, UK. [5] European Translational Oncology Prevention and Screening (EUTOPS) Institute, Universität Innsbruck, 6060, Hall in Tirol, Austria.;Research Institute for Biomedical Aging Research, Universität Innsbruck, 6020, Innsbruck, Austria. [6] Department of Applied Health Research, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK. [7] Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK, England. [8] University of Manchester, St. Mary's Hospital, and University Hospital of South Manchester, Manchester, UK. [9] Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.;Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, 98195, USA. [10] Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK, England.;Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK. [11] Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA. [12] Department of Pathology, Keck School of Medicine, USC/Norris Comprehensive Cancer Centre, University of Southern California, Los Angeles, USA. [13] Department of Women's Cancer, UCL EGA Institute for Women's Health, University College London, 74 Huntley Street, London, WC1E 6AU, UK. martin.widschwendter@uibk.ac.at.;European Translational Oncology Prevention and Screening (EUTOPS) Institute, Universität Innsbruck, 6060, Hall in Tirol, Austria. martin.widschwendter@uibk.ac.at.;Research Institute for Biomedical Aging Research, Universität Innsbruck, 6020, Innsbruck, Austria. martin.widschwendter@uibk.ac.at.;Department of Women's and Children's Health, Division of Obstetrics and Gynecology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. martin.widschwendter@uibk.ac.at. [14]
DOI 10.1186/s13073-022-01063-5
PMID 35701800
发布时间 2022-07-20
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