A cooperative mechanism of target RNA selection via germ-cell-specific RNA-binding proteins NANOS2 and DND1.

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作者： Takamasa,Hirano ^[1] ; Danelle,Wright ^[2] ; Atsushi,Suzuki ^[3] ; Yumiko,Saga ^[4]

作者单位： Mammalian Development Laboratory, Department of Gene Function and Phenomics, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan. ^[1] Mammalian Development Laboratory, Department of Gene Function and Phenomics, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan; Department of Genetics, SOKENDAI, 1111 Mishima, Shizuoka 411-8582, Japan. ^[2] Division of Materials Science and Chemical Engineering, Graduate School of Engineering, Yokohama National University, Yokohama, Kanagawa 240-8501 Japan. ^[3] Mammalian Development Laboratory, Department of Gene Function and Phenomics, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan; Department of Genetics, SOKENDAI, 1111 Mishima, Shizuoka 411-8582, Japan; Division for Development of Genetic-Engineered Mouse Resource, Genetic Resource Center, National Institute of Genetics, 1111 Mishima, Shizuoka 411-8582, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan. Electronic address: ysaga@nig.ac.jp. ^[4]

关键词 CNOT CP: Molecular biology Dnd1 Nanos2 P body RNA-binding protein deadenylation germ cell gonocyte post-transcriptional regulation spermatogonial stem cell