Sprouty-related proteins with EVH1 domain (SPRED2) prevents high-glucose induced endothelial-mesenchymal transition and endothelial injury by suppressing MAPK activation.

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作者： Tian,Liu ^[1] ; Jing,Zhao ^[2] ; Chengmin,Lin ^[2]

作者单位： Department of Ophthalmology, The First People's Hospital of Jingmen, Jingmen, China. ^[1] Department of Ophthalmology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, China. ^[2]

关键词 MAPK SPRED2 blood–retinal barrier injury diabetic retinopathy endothelial–mesenchymal transition

主题词动物(Animals);糖尿病视网膜病变(Diabetic Retinopathy);内皮细胞(Endothelial Cells);葡萄糖(Glucose);大鼠(Rats);视网膜(Retina);信号传导(Signal Transduction)

DOI 10.1080/21655979.2022.2086351

PMID 35707829

发布时间 2022-07-16

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Bioengineered

2022年13卷5期

13882-13892页

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Sprouty-related proteins with EVH1 domain (SPRED2) prevents high-glucose induced endothelial-mesenchymal transition and endothelial injury by suppressing MAPK activation.

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Sprouty-related proteins with EVH1 domain (SPRED2) prevents high-glucose induced endothelial-mesenchymal transition and endothelial injury by suppressing MAPK activation.

Bioengineered

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Bioengineered

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