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eQTL Set-Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma.

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作者: Xiaoyu,Wang [1] ; Puya,Gharahkhani [2] ; David M,Levine [3] ; Rebecca C,Fitzgerald [4] ; Ines,Gockel [5] ; Douglas A,Corley [6] ; Harvey A,Risch [7] ; Leslie,Bernstein [8] ; Wong-Ho,Chow [9] ; Lynn,Onstad [10] ; Nicholas J,Shaheen [1] ; Jesper,Lagergren [11] ; Laura J,Hardie [12] ; Anna H,Wu [13] ; Paul D P,Pharoah [14] ; Geoffrey,Liu [15] ; Lesley A,Anderson [16] ; Prasad G,Iyer [17] ; Marilie D,Gammon [18] ; Carlos,Caldas [19] ; Weimin,Ye [20] ; Hugh,Barr [21] ; Paul,Moayyedi [22] ; Rebecca,Harrison [12] ; R G Peter,Watson [23] ; Stephen,Attwood [24] ; Laura,Chegwidden [25] ; Sharon B,Love [26] ; David,MacDonald [27] ; John,deCaestecker [28] ; Hans,Prenen [29] ; Katja,Ott [30] ; Susanne,Moebus [31] ; Marino,Venerito [32] ; Hauke,Lang [33] ; Rupert,Mayershofer [34] ; Michael,Knapp [35] ; Lothar,Veits [36] ; Christian,Gerges [37] ; Josef,Weismüller [38] ; Matthias,Reeh [39] ; Markus M,Nöthen [40] ; Jakob R,Izbicki [41] ; Hendrik,Manner [42] ; Horst,Neuhaus [43] ; Thomas,Rösch [44] ; Anne C,Böhmer [45] ; Arnulf H,Hölscher [46] ; Mario,Anders [41] ; Oliver,Pech [47] ; Brigitte,Schumacher [44] ; Claudia,Schmidt [48] ; Thomas,Schmidt [47] ; Tania,Noder [49] ; Dietmar,Lorenz [50] ; Michael,Vieth [41] ; Andrea,May [51] ; Timo,Hess [52] ; Nicole,Kreuser [33] ; Jessica,Becker [47] ; Christian,Ell [53] ; Ian,Tomlinson [40] ; Claire,Palles [54] ; Janusz A,Jankowski [55] ; David C,Whiteman [5] ; Stuart,MacGregor [44] ; Johannes,Schumacher [56] ; Thomas L,Vaughan [57] ; Matthew F,Buas [58] ; James Y,Dai [59]
作者单位: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. [1] QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. [2] Department of Biostatistics, University of Washington, School of Public Health, Seattle, Washington. [3] Medical Research Council (MRC) Cancer Unit, Hutchison-MRC Research, Centre, University of Cambridge, Cambridge, UK. [4] Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany. [5] Division of Research, Kaiser Permanente Northern California, Oakland, California. [6] San Francisco Medical Center, Kaiser Permanente Northern California, San Francisco, California. [7] Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut. [8] Department of Population Sciences, Beckman Research Institute and City of Hope Comprehensive Cancer Center, Duarte, California. [9] Department of Epidemiology, MD Anderson Cancer Center, Houston, Texas. [10] Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, North Carolina. [11] Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden. [12] School of Cancer and Pharmaceutical Sciences, King's College London, London, UK. [13] Division of Epidemiology, University of Leeds, Leeds, UK. [14] Department of Population and Public Health Sciences, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California. [15] Department of Oncology, University of Cambridge, Cambridge, UK. [16] Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [17] Pharmacogenomic Epidemiology, Ontario Cancer Institute, Toronto, Ontario, Canada. [18] Department of Epidemiology and Public Health, Queen's University of Belfast, Royal Group of Hospitals, Northern Ireland. [19] Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. [20] Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina. [21] Cancer Research UK, Cambridge Institute, Cambridge, UK. [22] Department of Upper GI Surgery, Gloucestershire Royal Hospital, Gloucester, UK. [23] Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada. [24] Department of Pathology, Leicester Royal Infirmary, Leicester, UK. [25] Department of Medicine, Institute of Clinical Science, Royal Victoria Hospital, Belfast, UK. [26] Department of General Surgery, North Tyneside General Hospital, North Shields, UK. [27] University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [28] Centre for Statistics in Medicine and Oxford Clinical Trials Research Unit, Oxford, UK. [29] Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada. [30] Digestive Diseases Centre, University Hospitals of Leicester, Leicester, UK. [31] Oncology Department, University Hospital Antwerp, Edegem, Belgium. [32] Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany. [33] Department of General, Visceral and Thorax Surgery, RoMed Klinikum Rosenheim, Rosenheim, Germany. [34] Institute for Urban Public Health, University Hospitals, University of Duisburg-Essen, Essen, Germany. [35] Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University Hospital, Magdeburg, Germany. [36] Department of General, Visceral and Transplant Surgery, University Medical Center, University of Mainz, Mainz, Germany. [37] Gastroenterologie am Burgweiher, Bonn, Germany. [38] Institute for Medical Biometry, Informatics, and Epidemiology, University of Bonn, Bonn, Germany. [39] Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Klinikum Bayreuth, Bayreuth, Germany. [40] Department of Internal Medicine, Evangelisches Krankenhaus, Düsseldorf, Germany. [41] Gastroenterologische Gemeinschaftspraxis, Koblenz, Germany. [42] Department of General, Visceral and Thoracic Surgery, Asklepios Harzklinik Goslar, Goslar, Germany. [43] Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, Germany. [44] General, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [45] Department of Internal Medicine II, Frankfurt Hoechst Hospital, Frankfurt, Germany. [46] Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, Hamburg, Germany. [47] Clinic for General, Visceral and Trauma Surgery, Contilia Center for Esophageal Diseases, Elisabeth Hospital Essen, Germany. [48] Department of Gastroenterology and Interdisciplinary Endoscopy, Vivantes Wenckebach-Klinikum, Berlin, Germany. [49] Department of Gastroenterology and Interventional Endoscopy, St. John of God Hospital, Regensburg, Germany. [50] Department of Internal Medicine and Gastroenterology, Elisabeth Hospital, Essen, Germany. [51] Department of General, Visceral and Cancer Surgery, University of Cologne, Cologne, Germany. [52] Department of General and Visceral Surgery, Sana Klinikum, Offenbach, Germany. [53] Department of Gastroenterology, Oncology and Pneumology, Asklepios Paulinen Klinik, Wiesbaden, Germany. [54] Center for Human Genetics, University Hospital of Marburg, Marburg, Germany. [55] Department of Medicine II, Sana Klinikum, Offenbach, Germany. [56] Edinburgh Cancer Research Centre, IGMM, University of Edinburgh, Edinburgh, UK. [57] Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK. [58] Comprehensive Clinical Trials Unit, University College London, London, UK. [59] Cancer Control, QIMR Berghofer Medical Research Institute, Brisbane, Australia. [60] Department of Epidemiology, University of Washington, School of Public Health, Seattle, Washington. [61] Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York. [62]
DOI 10.1158/1055-9965.EPI-22-0096
PMID 35709760
发布时间 2024-03-13
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

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