SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ.
第一作者:
Tao,Yuan
第一单位:
Institute of Pharmacology & Toxicology , Zhejiang Province Key Laboratory of Anti-Cancer Drug Research , College of Pharmaceutical Sciences , Zhejiang University , Hangzhou , China.
作者:
主题词
人类(Humans);动物(Animals);小鼠(Mice);癌, 肝细胞(Carcinoma, Hepatocellular);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);肝肿瘤(Liver Neoplasms);反式激活因子类(Trans-Activators);琥珀酸盐(Succinates);电子传递复合物Ⅱ(Electron Transport Complex II)
DOI
10.1002/hep.32621
PMID
35713976
发布时间
2023-06-21
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Hepatology (Baltimore, Md.)
103-119页
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