An integrated genome and phenome-wide association study approach to understanding Alzheimer's disease predisposition.

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第一作者： Archita S,Khaire

第一单位： Division of Neuro-epidemiology, Department of Neurosurgery, Duke University, Durham, NC, USA.

作者： Archita S,Khaire ^[1] ; Courtney E,Wimberly ^[1] ; Eleanor C,Semmes ^[2] ; Jillian H,Hurst ^[3] ; Kyle M,Walsh ^[4]

作者单位： Division of Neuro-epidemiology, Department of Neurosurgery, Duke University, Durham, NC, USA. ^[1] Medical Scientist Training Program, Duke University, Durham, NC, USA; Children's Health and Discovery Initiative, Department of Pediatrics, Duke University, Durham, NC, USA. ^[2] Children's Health and Discovery Initiative, Department of Pediatrics, Duke University, Durham, NC, USA. ^[3] Division of Neuro-epidemiology, Department of Neurosurgery, Duke University, Durham, NC, USA; Children's Health and Discovery Initiative, Department of Pediatrics, Duke University, Durham, NC, USA; Center for the Study of Aging and Human Development, Duke University, Durham, NC, USA. Electronic address: kyle.walsh@duke.edu. ^[4]

关键词 Alzheimer's disease EGFR GWAS Genetic epidemiology PheWAS

主题词阿尔茨海默病(Alzheimer Disease);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);多态性, 单核苷酸(Polymorphism, Single Nucleotide)

DOI 10.1016/j.neurobiolaging.2022.05.011

PMID 35715361

发布时间 2023-10-02

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