Contextual generalization of social stress learning is modulated by orexin receptors in basolateral amygdala.
作者:
关键词
3'-[[[3-[[2-[[2-(Dimethylamino)benzoyl]amino]ethyl]amino]phenyl]amino]sulfonyl]-4′-methoxy-N,N-dimethyl-[1,1′-biphenyl]-3-carboxamide dihydrochloride5″-chloro-N-[(5,6-Dimethoxy-2-pyridinyl)methyl]-[2,2':5′,3″-terpyridine]-3′-carboxamideAn Orx(1)R plus Orx(2)R agonistAn Orx(2)An Orx(2) antagonistAn orexin 1 receptor [Orx(1)R] antagonistAnxietyDefeatDepressionFear conditioningFreezingHypocretinLocomotionMK-1064Orexin AOrx(A) & MK-1064PTSDPYR-PRO-LEU-PRO-ASP-CYS-CYS-ARG-GLN-LYS-THR-CYS-SER-CYS-ARG-LEU-TYR-GLU-LEU-LEU–HIS–GLY-ALA-GLY-ASN–HIS–ALA-ALA-GLY-ILE-LEU-THR-LEU-NH2ResilienceSB-674042Stress-alternatives modelSusceptibilityTargeted Orx(1)R stimulationTransferenceYNT-185[5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl-1-pyrrolidinyl]methanone
主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);回避学习(Avoidance Learning);小鼠(Mice);肽碎片(Peptide Fragments);社会行为(Social Behavior);胰蛋白酶(Trypsin)
DOI
10.1016/j.neuropharm.2022.109168
PMID
35724928
发布时间
2022-09-02
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Neuropharmacology
109168页
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