Identification of a distal enhancer that determines the expression pattern of acute phase marker C-reactive protein.

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作者： Ming-Yu,Wang ^[1] ; Chun-Miao,Zhang ^[1] ; Hai-Hong,Zhou ^[2] ; Zhong-Bo,Ge ^[1] ; Chen-Chen,Su ^[1] ; Zi-Hao,Lou ^[1] ; Xin-Yun,Zhang ^[1] ; Tao-Tao,Xu ^[1] ; Si-Yi,Li ^[1] ; Li,Zhu ^[3] ; Ya-Li,Zhou ^[4] ; Yi,Wu ^[5] ; Shang-Rong,Ji ^[6]

作者单位： MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, P. R. China. ^[1] Translational Medicine Research Center, Gansu Provincial Cancer Hospital, Lanzhou, P. R. China. ^[2] MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, P. R. China; Electron Microscopy Centre, Lanzhou University, Lanzhou, P. R. China. ^[3] Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, P. R. China. ^[4] MOE Key Laboratory of Environment and Genes Related to Diseases, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China; Key Laboratory of Precision Medicine to Pediatric Diseases of Shaanxi Province, Xi'an Children's Hospital, Xi'an Jiaotong University, Xi'an, P. R. China. Electronic address: wuy@lzu.edu.cn. ^[5] MOE Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, P. R. China. Electronic address: jsr@lzu.edu.cn. ^[6]

关键词 C-reactive protein STAT3 acute phase response enhancer evolution inflammation