Cryo-EM structures of SARS-CoV-2 Omicron BA.2 spike.

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第一作者： Victoria,Stalls

第一单位： Duke Human Vaccine Institute, Durham, NC 27710, USA.

作者： Victoria,Stalls ^[1] ; Jared,Lindenberger ^[1] ; Sophie M-C,Gobeil ^[1] ; Rory,Henderson ^[2] ; Rob,Parks ^[1] ; Maggie,Barr ^[1] ; Margaret,Deyton ^[1] ; Mitchell,Martin ^[1] ; Katarzyna,Janowska ^[1] ; Xiao,Huang ^[1] ; Aaron,May ^[3] ; Micah,Speakman ^[1] ; Esther,Beaudoin ^[1] ; Bryan,Kraft ^[4] ; Xiaozhi,Lu ^[1] ; Robert J,Edwards ^[2] ; Amanda,Eaton ^[1] ; David C,Montefiori ^[5] ; Wilton B,Williams ^[3] ; Kevin O,Saunders ^[5] ; Kevin,Wiehe ^[2] ; Barton F,Haynes ^[6] ; Priyamvada,Acharya ^[7]

作者单位： Duke Human Vaccine Institute, Durham, NC 27710, USA. ^[1] Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Medicine, Duke University, Durham, NC 27710, USA. ^[2] Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Biochemistry, Duke University, Durham, NC 27710, USA. ^[3] Department of Medicine, Duke University, Durham, NC 27710, USA. ^[4] Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Surgery, Duke University, Durham, NC 27710, USA. ^[5] Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Medicine, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University, Durham, NC 27710, USA. Electronic address: barton.haynes@duke.edu. ^[6] Duke Human Vaccine Institute, Durham, NC 27710, USA; Department of Biochemistry, Duke University, Durham, NC 27710, USA; Department of Surgery, Duke University, Durham, NC 27710, USA. Electronic address: priyamvada.acharya@duke.edu. ^[7]

关键词 CP: Microbiology Omicron BA.2 SARS-CoV-2 spike cryoelectron microscopy fusion peptide immune evasion receptor binding domain

主题词抗体, 病毒(Antibodies, Viral);冷冻电子显微镜检查(Cryoelectron Microscopy);人类(Humans);受体, 病毒(Receptors, Virus)

DOI 10.1016/j.celrep.2022.111009

PMID 35732171

发布时间 2024-09-23

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