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首页> Tuberculosis (Edinburgh, Scotland)> A high content screening assay for discovery of antimycobacterial compounds based on primary human macrophages infected with virulent Mycobacterium tuberculosis.

A high content screening assay for discovery of antimycobacterial compounds based on primary human macrophages infected with virulent Mycobacterium tuberculosis.

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作者： Sadaf,Kalsum ^[1] ; Magdalena,Otrocka ^[2] ; Blanka,Andersson ^[1] ; Amanda,Welin ^[1] ; Thomas,Schön ^[3] ; Annika,Jenmalm-Jensen ^[2] ; Thomas,Lundbäck ^[2] ; Maria,Lerm ^[4]

作者单位： Division of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Sweden. ^[1] Chemical Biology Consortium Sweden, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Sweden. ^[2] Division of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Sweden; Departments of Infectious Diseases, Kalmar County Hospital, Kalmar Sweden and Linköping University Hospital, Linköping, Sweden. ^[3] Division of Inflammation and Infection, Department of Biomedical and Clinical Sciences, Linköping University, Sweden. Electronic address: maria.lerm@liu.se. ^[4]

关键词 High content screening Mycobacterium tuberculosis Phenotypic assay Primary human monocyte-derived macrophages

主题词抗结核药(Antitubercular Agents);人类(Humans);异烟肼(Isoniazid);巨噬细胞(Macrophages);结核分枝杆菌(Mycobacterium tuberculosis);结果可重复性(Reproducibility of Results);利福平(Rifampin);结核, 淋巴结(Tuberculosis, Lymph Node)

DOI 10.1016/j.tube.2022.102222

PMID 35738191

发布时间 2022-08-29

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Tuberculosis (Edinburgh, Scotland)

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