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Genomic Aberrations in Circulating Tumor DNAs from Palbociclib-Treated Metastatic Breast Cancer Patients Reveal a Novel Resistance Mechanism.

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第一作者： Maysa,Abu-Khalaf

第一单位： Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

作者： Maysa,Abu-Khalaf ^[1] ; Chun,Wang ^[1] ; Zhenchao,Zhang ^[1] ; Rui,Luo ^[1] ; Weelic,Chong ^[1] ; Daniel P,Silver ^[1] ; Frederick,Fellin ^[1] ; Rebecca,Jaslow ^[1] ; AnaMaria,Lopez ^[1] ; Terrence,Cescon ^[2] ; Wei,Jiang ^[3] ; Ronald,Myers ^[1] ; Qiang,Wei ^[4] ; Bingshan,Li ^[4] ; Massimo,Cristofanilli ^[5] ; Hushan,Yang ^[1]

作者单位： Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. ^[1] Department of Hematology Oncology, Reading Hospital, West Reading, PA 19611, USA. ^[2] Department of Pathology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. ^[3] Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37235, USA. ^[4] Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA. ^[5]

关键词 circulating tumor DNA metastatic breast cancer palbociclib somatic mutation treatment resistance

DOI 10.3390/cancers14122872

PMID 35740538

发布时间 2022-12-17

基金项目

R01 CA207468/CA/NCI NIH HHS/United States R01 CA255792/CA/NCI NIH HHS/United States R01CA207468/CA/NCI NIH HHS/United States

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