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High Incidence of SARS-CoV-2 Variant of Concern Breakthrough Infections Despite Residual Humoral and Cellular Immunity Induced by BNT162b2 Vaccination in Healthcare Workers: A Long-Term Follow-Up Study in Belgium.

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第一作者： Bas,Calcoen

第一单位： Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, 8500 Kortrijk, Belgium.

作者： Bas,Calcoen ^[1] ; Nico,Callewaert ^[2] ; Aline,Vandenbulcke ^[1] ; Winnie,Kerstens ^[3] ; Maya,Imbrechts ^[4] ; Thomas,Vercruysse ^[3] ; Kai,Dallmeier ^[5] ; Johan,Van Weyenbergh ^[6] ; Piet,Maes ^[6] ; Xavier,Bossuyt ^[7] ; Dorinja,Zapf ^[8] ; Kersten,Dieckmann ^[8] ; Kim,Callebaut ^[2] ; Hendrik Jan,Thibaut ^[3] ; Karen,Vanhoorelbeke ^[9] ; Simon F,De Meyer ^[1] ; Wim,Maes ^[4] ; Nick,Geukens ^[4]

作者单位： Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, 8500 Kortrijk, Belgium. ^[1] AZ Groeninge Hospital, Department of Laboratory Medicine, 8500 Kortrijk, Belgium. ^[2] Laboratory of Virology and Chemotherapy, Translational Platform Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, KU Leuven Rega Institute, 3000 Leuven, Belgium. ^[3] PharmAbs, the KU Leuven Antibody Center, KU Leuven, 3000 Leuven, Belgium. ^[4] Laboratory of Virology, Molecular Vaccinology and Vaccine Discovery, Department of Microbiology, Immunology and Transplantation, KU Leuven Rega Institute, 3000 Leuven, Belgium. ^[5] Laboratory for Clinical and Epidemiological Virology, KU Leuven Rega Institute, 3000 Leuven, Belgium. ^[6] Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium.;Department of Laboratory Medicine, University Hospitals Leuven, 3000 Leuven, Belgium. ^[7] Institut für Experimentelle Immunologie, EUROIMMUN Medizinische Labordiagnostika AG, 23552 Lübeck, Germany. ^[8] Laboratory for Thrombosis Research, KU Leuven Campus Kulak Kortrijk, 8500 Kortrijk, Belgium.;PharmAbs, the KU Leuven Antibody Center, KU Leuven, 3000 Leuven, Belgium. ^[9]

关键词 BNT162b2 vaccine SARS-CoV-2 breakthrough infection healthcare workers long-term monitoring variants of concern