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Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study.

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第一作者： Nadine,Saul

第一单位： Molecular Genetics Group, Institute of Biology, Humboldt University of Berlin, Berlin, Germany. nadine.saul@gmx.de.

作者： Nadine,Saul ^[1] ; Ineke,Dhondt ^[2] ; Mikko,Kuokkanen ^[3] ; Markus,Perola ^[4] ; Clara,Verschuuren ^[2] ; Brecht,Wouters ^[5] ; Henrik,von Chrzanowski ^[6] ; Winnok H,De Vos ^[7] ; Liesbet,Temmerman ^[5] ; Walter,Luyten ^[5] ; Aleksandra,Zečić ^[2] ; Tim,Loier ^[2] ; Christian,Schmitz-Linneweber ^[8] ; Bart P,Braeckman ^[2]

作者单位： Molecular Genetics Group, Institute of Biology, Humboldt University of Berlin, Berlin, Germany. nadine.saul@gmx.de. ^[1] Laboratory of Aging Physiology and Molecular Evolution, Biology Department, Ghent University, Ghent, Belgium. ^[2] Genomics and Biomarkers Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland.;Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA. ^[3] Genomics and Biomarkers Unit, Department of Health, National Institute for Health and Welfare, Helsinki, Finland. ^[4] Biology Department, KU Leuven, Leuven, Belgium. ^[5] Molecular Genetics Group, Institute of Biology, Humboldt University of Berlin, Berlin, Germany.;The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel. ^[6] Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium. ^[7] Molecular Genetics Group, Institute of Biology, Humboldt University of Berlin, Berlin, Germany. ^[8]

关键词 Ageing C. elegans GWAS Healthspan Muscle integrity Stress resistance