Targeting inflamed and non-inflamed melanomas: biological background and clinical challenges.

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第一作者： Alice,Indini

第一单位： Division of Medical Oncology, Department of Medicine and Surgery, Ospedale di Circolo e Fondazione Macchi, ASST dei Sette Laghi, Varese, Italy.

作者： Alice,Indini ^[1] ; Daniela,Massi ^[2] ; Matteo,Pirro ^[3] ; Fausto,Roila ^[4] ; Francesco,Grossi ^[5] ; Amirhossein,Sahebkar ^[6] ; Nicole,Glodde ^[7] ; Tobias,Bald ^[7] ; Mario,Mandalà ^[8]

作者单位： Division of Medical Oncology, Department of Medicine and Surgery, Ospedale di Circolo e Fondazione Macchi, ASST dei Sette Laghi, Varese, Italy. ^[1] Section of Pathological Anatomy, Department of Health Sciences, University of Florence, Florence, Italy. ^[2] University of Perugia, Department of Medicine and Surgery, Unit of Internal Medicine, Perugia, Italy. ^[3] University of Perugia, Department of Surgery and Medicine, Unit of Medical Oncology, Perugia, Italy. ^[4] Division of Medical Oncology, Department of Medicine and Surgery, Ospedale di Circolo e Fondazione Macchi, ASST dei Sette Laghi, Varese, Italy; Division of Medical Oncology, University of Insubria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy. ^[5] Biotechnology Research Center, Pharmaceutical Technology Institute &amp; Neurogenic Inflammation Research Center &amp; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. ^[6] Laboratory of Tumor-Immunobiology, Institute of Experimental Oncology (IEO), University Hospital Bonn, University of Bonn, Bonn, Germany. ^[7] University of Perugia, Department of Surgery and Medicine, Unit of Medical Oncology, Perugia, Italy. Electronic address: mario.mandala@unipg.it. ^[8]

关键词 Gene expression profile Immunotherapy Inflamed Melanoma Non-inflamed

主题词人类(Humans);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);免疫疗法(Immunotherapy);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);肿瘤微环境(Tumor Microenvironment);黑色素瘤(Melanoma);免疫因子类(Immunologic Factors)

DOI 10.1016/j.semcancer.2022.06.005

PMID 35752398

发布时间 2022-12-22

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