Mucus-Penetrating Alginate-Chitosan Nanoparticles Loaded with Berberine Hydrochloride for Oral Delivery to the Inflammation Site of Ulcerative Colitis.

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作者： Lingfeng,Sun ^[1] ; Xiangjiang,Nie ^[1] ; Wenjie,Lu ^[2] ; Qing,Zhang ^[3] ; Wenyou,Fang ^[1] ; Song,Gao ^[4] ; Shengqi,Chen ^[5] ; Rongfeng,Hu ^[6]

作者单位： Anhui Province Key Laboratory of Pharmaceutical Technology and Application, Key Laboratory of Xin'an Medicine Ministry of Education, Anhui Province Key Laboratory of Chinese Medicinal Formula, Anhui University of Chinese Medicine, Hefei, 230038, Anhui, China. ^[1] School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, Jiangsu, China. ^[2] Department of Pharmacy, School of Pharmacy, Nanjing Medical University, Nanjing, 210009, Jiangsu, China. ^[3] Anhui Province Key Laboratory of Pharmaceutical Technology and Application, Key Laboratory of Xin'an Medicine Ministry of Education, Anhui Province Key Laboratory of Chinese Medicinal Formula, Anhui University of Chinese Medicine, Hefei, 230038, Anhui, China. 28552806@qq.com. ^[4] Anhui Province Key Laboratory of Pharmaceutical Technology and Application, Key Laboratory of Xin'an Medicine Ministry of Education, Anhui Province Key Laboratory of Chinese Medicinal Formula, Anhui University of Chinese Medicine, Hefei, 230038, Anhui, China. sqchen@ahtcm.edu.cn. ^[5] Anhui Province Key Laboratory of Pharmaceutical Technology and Application, Key Laboratory of Xin'an Medicine Ministry of Education, Anhui Province Key Laboratory of Chinese Medicinal Formula, Anhui University of Chinese Medicine, Hefei, 230038, Anhui, China. rongfenghu2003@hotmail.com. ^[6]

关键词 berberine hydrochloride chitosan mucus-penetrating oral colon-targeted drug delivery system ulcerative colitis