Fitting Pharmacodynamic Data to the Emax Model to Assess the Inherent Potency of Topical Corticosteroids.

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作者： Pronalis,Tapfumaneyi ^[1] ; Seeprarani,Rath ^[1] ; Charles,Bon ^[2] ; Isadore,Kanfer ^[1]

作者单位： Biopharmaceutics Research Institute, Rhodes University, Grahamstown 6139, South Africa. ^[1] Biostudy Solutions LLC, Wilmington, North Carolina 28401, United States. ^[2] Leslie Dan College of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada. ^[3]

关键词 Emax model active pharmaceutical ingredients chromameter potency classification skin blanching topical corticosteroids vasoconstrictor assay

主题词投药, 局部(Administration, Topical);肾上腺皮质激素类(Adrenal Cortex Hormones);皮肤科用药(Dermatologic Agents);糖皮质激素类(Glucocorticoids);人类(Humans)

DOI 10.1021/acs.molpharmaceut.2c00254

PMID 35763717

发布时间 2022-08-03

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