MBZM-N-IBT, a Novel Small Molecule, Restricts Chikungunya Virus Infection by Targeting nsP2 Protease Activity In Vitro, In Vivo, and Ex Vivo.

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第一作者： Saikat,De

第一单位： Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.;Regional Centre for Biotechnology, Faridabad, Haryana, India.

作者： Saikat,De ^[1] ; Soumyajit,Ghosh ^[1] ; Supriya Suman,Keshry ^[2] ; Chandan,Mahish ^[3] ; Chinmayee,Mohapatra ^[4] ; Ankeeta,Guru ^[1] ; Prabhudutta,Mamidi ^[4] ; Ankita,Datey ^[2] ; Sweta Smita,Pani ^[4] ; Dileep,Vasudevan ^[4] ; Tushar Kant,Beuria ^[4] ; Subhasis,Chattopadhyay ^[5] ; Bharat Bhusan,Subudhi ^[6] ; Soma,Chattopadhyay ^[4]

作者单位： Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.;Regional Centre for Biotechnology, Faridabad, Haryana, India. ^[1] Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India.;School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, Odisha, India. ^[2] National Institute of Science Education and Research, Bhubaneswar, Odisha, India.;Homi Bhabha National Institute, Training School Complex, Mumbai, Maharashtra, India. ^[3] Institute of Life Sciencesgrid.418782.0, Bhubaneswar, Odisha, India. ^[4] National Institute of Science Education and Research, Bhubaneswar, Odisha, India. ^[5] School of Pharmaceutical Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha, India. ^[6]

关键词 Chikungunya anti-viral infection inflammation replication