Optimization of Recombinant GPCR Proteins for Biophysical and Structural Studies Using Virus-like Particles.

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第一作者： Kathleen,Aertgeerts

第一单位： Biology Department, Vertex Pharmaceuticals, San Diego, CA, USA. Kathleen_aertgeerts@vrtx.com.

作者： Kathleen,Aertgeerts ^[1] ; Thao T,Ho ^[2] ; Yingzhou G,Yan ^[3]

作者单位： Biology Department, Vertex Pharmaceuticals, San Diego, CA, USA. Kathleen_aertgeerts@vrtx.com. ^[1] Biology Department, Vertex Pharmaceuticals, San Diego, CA, USA. ^[2] Neuroscience TRC, Bristol Myers Squibb, San Diego, CA, USA. ^[3]

关键词 G-Protein Coupled Receptor GPCR Integral Membrane Proteins Protein Engineering Protein Stabilization Virus-like Particles

主题词生物物理学(Biophysics);色谱法, 亲和(Chromatography, Affinity);基因表达(Gene Expression);配体(Ligands);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);重组蛋白质类(Recombinant Proteins)

DOI 10.1007/978-1-0716-2368-8_17

PMID 35773590

发布时间 2022-08-15

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准确一般字义偏差语意偏离译文作用小提交