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SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates.

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作者单位: Cell Fate Engineering and Therapeutics Lab, Cell Biology and Therapies Division, A*STAR Institute of Molecular and Cell Biology, Singapore 138673, Singapore. [1] Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore. [2] School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore. [3] Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore. [4] Proteomics Group, Bioprocessing Technology Institute, A*STAR, Singapore 138668, Singapore. [5] Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672, Singapore. [6] Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore. [7] Infectious Disease Translational Research Programme, National University of Singapore, Singapore 117597, Singapore. [8] Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore. [9] Howard Hughes Medical Institute, Boston, MA 02114, USA. [10] Institute for Medical Engineering and Science Department of Biological Engineering, and Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, MA 02114, USA. [11] Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA. [12] Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. [13] Center for Individualized Medicine, Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA. [14] Department of Plant Systems Physiology, Radboud Institute for Biological and Environmental Sciences, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. [15] NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, 28 MedicalDrive, Singapore 117456, Singapore. [16]
DOI 10.1093/nar/gkac531
PMID 35776115
发布时间 2023-12-13
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