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首页> PloS one> Integration of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation.

Integration of bioassay and non-target metabolite analysis of tomato reveals that β-carotene and lycopene activate the adiponectin signaling pathway, including AMPK phosphorylation.

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作者： Shinsuke,Mohri ^[1] ; Haruya,Takahashi ^[2] ; Maiko,Sakai ^[1] ; Naoko,Waki ^[3] ; Shingo,Takahashi ^[1] ; Koichi,Aizawa ^[3] ; Hiroyuki,Suganuma ^[4] ; Takeshi,Ara ^[4] ; Tatsuya,Sugawara ^[4] ; Daisuke,Shibata ^[4] ; Yasuki,Matsumura ^[3] ; Tsuyoshi,Goto ^[2] ; Teruo,Kawada ^[3]

作者单位： Laboratory of Molecular Function of Food, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. ^[1] Laboratory of Technology of Marine Bioproducts, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. ^[2] KAGOME Tomato Discoveries Laboratory, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. ^[3] Innovation Division, KAGOME CO., LTD., Tochigi, Japan. ^[4] Kazusa DNA Research Institutes, Kazusa-Kamatari, Chiba, Japan. ^[5] Laboratory of Quality Analysis and Assessment, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. ^[6] Research Unit for Physiological Chemistry, Kyoto University, Kyoto, Japan. ^[7]

主题词 AMP活化蛋白激酶类(AMP-Activated Protein Kinases);腺苷酸激酶(Adenylate Kinase);脂联素(Adiponectin);生物学鉴定法(Biological Assay);钙(Calcium);磷酰化(Phosphorylation);RNA, 小分子干扰(RNA, Small Interfering);受体, 脂联素(Receptors, Adiponectin);信号传导(Signal Transduction);β胡萝卜素(beta Carotene)

DOI 10.1371/journal.pone.0267248

PMID 35776737

发布时间 2022-12-07

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PloS one

PloS one

2022年17卷7期

e0267248页

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