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Identification of SHCBP1 as a potential biomarker involving diagnosis, prognosis, and tumor immune microenvironment across multiple cancers.

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第一作者: Ning,Wang
第一单位: Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000, PR China.
作者: Ning,Wang [1] ; Lingye,Zhu [1] ; Liangxing,Wang [1] ; Zhifa,Shen [2] ; Xiaoying,Huang [1]
作者单位: Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang 325000, PR China. [1] Key Laboratory of Laboratory Medicine, Ministry of Education of China, Zhejiang Provincial Key Laboratory of Medical Genetics, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China. [2]
关键词 3D, three-dimensionalACC, adrenocortical carcinomaAUC, area under the curveBLCA, bladder urothelial carcinomaBRCA, breast invasive carcinomaBiomarkerCAF, cancer-associated fibroblastsCCLE, cancer cell line encyclopediaCESC, cervical squamous cell carcinoma and endocervical adenocarcinomaCHOL, cholangiocarcinomaCOAD, colon adenocarcinomaDEGs, differentially expressed genesDFS, disease free survivalDLBC, lymphoid neoplasm diffuse large B-cell lymphomaDSS, disease specific survivalDiagnosisER, endoplasmic reticulumESCA, esophageal carcinomaGBM, glioblastoma multiformeGO, Gene OntologyGSEA, Gene Set Enrichment AnalysisGTEx, genotype-tissue expressionHNSC, head and neck squamous cell carcinomaHR, hazard ratioICIs, immune checkpoint inhibitorsImmuno-oncologyKEGG, Kyoto encyclopedia of genes and genomesKICH, kidney chromophobeKIRC, kidney renal clear cell carcinomaKIRP, kidney renal papillary cell carcinomaLAML, acute myeloid leukemiaLGG, brain lower grade gliomaLIHC, liver hepatocellular carcinomaLUAD, lung adenocarcinomaLUSC, lung squamous cell carcinomaMDSC, myeloid-derived suppressor cellsMESO, mesotheliomaMSI, microsatellite instabilityOS, overall survivalOV, ovarian serous cystadenocarcinomaPAAD, pancreatic adenocarcinomaPCPG, pheochromocytoma and paragangliomaPFS, progression free survivalPPI, protein–protein interactionPRAD, prostate adenocarcinomaPan-cancerPrognosisREAD, rectum adenocarcinomaROC, receiver operating characteristicSARC, sarcomaSHCBP1SHCBP1, Shc SH2-domain binding protein 1SKCM, skin cutaneous melanomaSTAD, stomach adenocarcinomaTAM, tumor-associated macrophagesTCGA, the cancer genome atlasTGCT, testicular germ cell tumorsTHCA, thyroid carcinomaTHPA, the human protein atlasTHYM, thymomaTIME, tumor immune microenvironmentTIMER 2.0, tumor immune estimation resource, version 2TMB, tumor mutational burdenUCEC, uterine corpus endometrial carcinomaUCS, uterine carcinosarcomaUVM, uveal melanoma
DOI 10.1016/j.csbj.2022.06.039
PMID 35782736
发布时间 2022-07-16
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Computational and structural biotechnology journal

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