Machine learning-guided evaluation of extraction and simulation methods for cancer patient-specific metabolic models.
第一作者:
Sang Mi,Lee
第一单位:
Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
作者:
关键词
1D CNN, one-dimensional convolutional neural networkCancer patient-specific metabolic modelE-Flux2, E-Flux method combined with minimization of L2normEvaluationFBA, flux balance analysisGEM, genome-scale metabolic modelGIMME, Gene Inactivity Moderated by Metabolism and ExpressionGPR, gene-protein-reactionGenome-scale metabolic modelLAD, least absolute deviationMEM, model extraction methodMSM, model simulation methodMachine learningModel extraction methodModel simulation methodSPOT, Simplified Pearson cOrrelation with Transcriptomic datapFBA, parsimonious flux balance analysist-SNE, t-distributed stochastic neighbor embeddingtINIT, task-driven Integrative Network Inference for Tissues
DOI
10.1016/j.csbj.2022.06.027
PMID
35782748
发布时间
2022-07-16
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