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Myeloid Cell Classification and Therapeutic Opportunities Within the Glioblastoma Tumor Microenvironment in the Single Cell-Omics Era.

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第一作者： Collin J,Larkin

第一单位： Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.

作者： Collin J,Larkin ^[1] ; Víctor A,Arrieta ^[2] ; Hinda,Najem ^[3] ; Gongbo,Li ^[3] ; Peng,Zhang ^[3] ; Jason,Miska ^[3] ; Peiwen,Chen ^[3] ; Charles David,James ^[3] ; Adam M,Sonabend ^[3] ; Amy B,Heimberger ^[3]

作者单位： Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. ^[1] Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.;Lou and Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.;Programa de Estudios Combinados en Medicina (PECEM), Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico. ^[2] Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.;Lou and Jean Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. ^[3]

关键词 glioblastoma immunotherapy macrophage single cell analysis spatial analysis transcriptomics tumor microenvironment

医学主题词胶质母细胞瘤(Glioblastoma);神经胶质瘤(Glioma);人类(Humans);髓系细胞(Myeloid Cells);骨髓祖代细胞(Myeloid Progenitor Cells);肿瘤微环境(Tumor Microenvironment)

DOI 10.3389/fimmu.2022.907605

PMID 35784281

发布时间 2022-07-18

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