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Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing.

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第一作者： Thomas R,Austin

第一单位： Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA. austintr@uw.edu.;Department of Epidemiology, University of Washington, Seattle, WA, USA. austintr@uw.edu.

作者： Thomas R,Austin ^[1] ; Caitlin P,McHugh ^[2] ; Jennifer A,Brody ^[3] ; Joshua C,Bis ^[3] ; Colleen M,Sitlani ^[3] ; Traci M,Bartz ^[4] ; Mary L,Biggs ^[5] ; Nisha,Bansal ^[6] ; Petra,Buzkova ^[7] ; Steven A,Carr ^[8] ; Christopher R,deFilippi ^[9] ; Mitchell S V,Elkind ^[10] ; Howard A,Fink ^[11] ; James S,Floyd ^[12] ; Alison E,Fohner ^[13] ; Robert E,Gerszten ^[14] ; Susan R,Heckbert ^[15] ; Daniel H,Katz ^[14] ; Jorge R,Kizer ^[16] ; Rozenn N,Lemaitre ^[3] ; W T,Longstreth ^[17] ; Barbara,McKnight ^[18] ; Hao,Mei ^[19] ; Kenneth J,Mukamal ^[20] ; Anne B,Newman ^[21] ; Debby,Ngo ^[20] ; Michelle C,Odden ^[22] ; Ramachandran S,Vasan ^[23] ; Ali,Shojaie ^[7] ; Noah,Simon ^[7] ; George Davey,Smith ^[24] ; Neil M,Davies ^[25] ; David S,Siscovick ^[26] ; Nona,Sotoodehnia ^[27] ; Russell P,Tracy ^[28] ; Kerri L,Wiggins ^[3] ; Jie,Zheng ^[24] ; Bruce M,Psaty ^[29]

作者单位： Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA. austintr@uw.edu.;Department of Epidemiology, University of Washington, Seattle, WA, USA. austintr@uw.edu. ^[1] Alzheimer's Disease Data Initiative, Kirkland, WA, USA. ^[2] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Medicine, University of Washington, Seattle, WA, USA. ^[3] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Medicine, University of Washington, Seattle, WA, USA.;Department of Biostatistics, University of Washington, Seattle, WA, USA. ^[4] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Biostatistics, University of Washington, Seattle, WA, USA. ^[5] Division of Nephrology, University of Washington, Seattle, WA, USA. ^[6] Department of Biostatistics, University of Washington, Seattle, WA, USA. ^[7] Broad Institute of MIT and Harvard, Boston, MA, USA. ^[8] Inova Heart and Vascular Institute, Falls Church, VA, USA. ^[9] Department of Neurology, Columbia University, New York, NY, USA. ^[10] Geriatric Research Education & Clinical Center, Minneapolis VA Healthcare System, Minneapolis, MN, USA. ^[11] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Epidemiology, University of Washington, Seattle, WA, USA.;Department of Medicine, University of Washington, Seattle, WA, USA. ^[12] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Epidemiology, University of Washington, Seattle, WA, USA.;Institute of Public Health Genetics, University of Washington, Seattle, WA, USA. ^[13] Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. ^[14] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Epidemiology, University of Washington, Seattle, WA, USA. ^[15] Cardiology Section, San Francisco VA Health Care System, San Francisco, CA, USA.;Department of Biostatistics, University of California San Francisco, San Francisco, CA, USA.;Department of Epidemology, University of California San Francisco, San Francisco, CA, USA.;Department of Medicine, University of California San Francisco, San Francisco, CA, USA. ^[16] Department of Epidemiology, University of Washington, Seattle, WA, USA.;Department of Neurology, University of Washington, Seattle, WA, USA. ^[17] Department of Medicine, University of Washington, Seattle, WA, USA. ^[18] Department of Data Science, University of Mississippi Medical Center, Jackson, MS, USA. ^[19] Beth Israel Deaconess Medical Center, Boston, MA, USA. ^[20] Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA. ^[21] Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA. ^[22] Department of Epidemiology, School of Public Health, Boston University, Boston, MA, USA.;Department of Medicine, Boston University School of Medicine, Boston, MA, USA. ^[23] MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK. ^[24] MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK.;K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Norwegian, Norway.;Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK. ^[25] The New York Academy of Medicine, New York, NY, USA. ^[26] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Division of Cardiology, University of Washington, Seattle, WA, USA. ^[27] Departments of Pathology & Laboratory Medicine, and Biochemistry, Larner College of Medicine, University of Vermont, Burlington, VT, USA. ^[28] Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.;Department of Epidemiology, University of Washington, Seattle, WA, USA.;Department of Medicine, University of Washington, Seattle, WA, USA.;Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA. ^[29]

关键词 Cardiovascular Disease Cohort Study Genomics Proteomics

医学主题词队列研究(Cohort Studies);女(雌)性(Female);人类(Humans);信息传播(Information Dissemination);男(雄)性(Male);前瞻性研究(Prospective Studies);蛋白质组学(Proteomics)

DOI 10.1007/s10654-022-00888-z

PMID 35790642

发布时间 2025-05-30

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