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Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation.

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第一作者： Federica,Rey

第一单位： Department of Biomedical and Clinical Sciences, University of Milano, Milano, Italy.;Department of Biomedical and Clinical Sciences, Pediatric Research Center "Romeo ed Enrica Invernizzi," University of Milano, Milano, Italy.

作者： Federica,Rey ^[1] ; Letizia,Messa ^[1] ; Erika,Maghraby ^[1] ; Giovanna,Casili ^[2] ; Sara,Ottolenghi ^[3] ; Bianca,Barzaghini ^[4] ; Manuela Teresa,Raimondi ^[4] ; Cristina,Cereda ^[5] ; Salvatore,Cuzzocrea ^[2] ; Gianvincenzo,Zuccotti ^[6] ; Emanuela,Esposito ^[2] ; Irene,Paterniti ^[2] ; Stephana,Carelli ^[1]

作者单位： Department of Biomedical and Clinical Sciences, University of Milano, Milano, Italy.;Department of Biomedical and Clinical Sciences, Pediatric Research Center "Romeo ed Enrica Invernizzi," University of Milano, Milano, Italy. ^[1] Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy. ^[2] Department of Medicine and Surgery, University of Milano Bicocca, Milano, Italy. ^[3] Department of Chemistry, Materials and Chemical Engineering "Giulio Natta," Politecnico di Milano, Milano, Italy. ^[4] Department of Women, Mothers and Neonatal Care, Children's Hospital "V. Buzzi," Milano, Italy. ^[5] Department of Biomedical and Clinical Sciences, University of Milano, Milano, Italy.;Department of Biomedical and Clinical Sciences, Pediatric Research Center "Romeo ed Enrica Invernizzi," University of Milano, Milano, Italy.;Department of Pediatrics, Children's Hospital "V. Buzzi," Milano, Italy. ^[6]

关键词 HIF-1 evaluation of oxygenation gene expression neurodegenerative diseases oxygen sensing oxygen-targeting drugs

主题词人类(Humans);氧(Oxygen);神经变性疾病(Neurodegenerative Diseases);活性氧(Reactive Oxygen Species);高氧症(Hyperoxia)

DOI 10.1089/ars.2022.0046

PMID 35793106

发布时间 2023-02-09

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