An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition.

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第一作者： Yijie,Sun

第一单位： National Centre for International Research in Cell and Gene Therapy, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China.

作者： Yijie,Sun ^[1] ; Zhe,Zhang ^[1] ; Chenglin,Zhang ^[1] ; Na,Zhang ^[1] ; Pengju,Wang ^[1] ; Yongchao,Chu ^[1] ; Louisa S,Chard Dunmall ^[2] ; Nicholas R,Lemoine ^[3] ; Yaohe,Wang ^[3]

作者单位： National Centre for International Research in Cell and Gene Therapy, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China. ^[1] Centre for Cancer Biomarkers & Biotherapeutics, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK. ^[2] National Centre for International Research in Cell and Gene Therapy, School of Basic Medical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450052, China.;Centre for Cancer Biomarkers & Biotherapeutics, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK. ^[3]

关键词 IL-21 anti-tumor immunity glioblastoma intravenous injection oncolytic vaccinia virus α-PD1

DOI 10.1016/j.omto.2022.05.008

PMID 35795092

发布时间 2024-08-30

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Molecular therapy oncolytics

2022年26卷

105-119页

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An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition.

Molecular therapy oncolytics

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Molecular therapy oncolytics

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An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition.

Molecular therapy oncolytics

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Molecular therapy oncolytics

相关期刊

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