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The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study.

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第一作者： Isabelle F,Foote

第一单位： Centre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, London, UK; Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. Electronic address: isabelle.foote@colorado.edu.

作者： Isabelle F,Foote ^[1] ; Benjamin M,Jacobs ^[2] ; Georgina,Mathlin ^[3] ; Cameron J,Watson ^[2] ; Phazha Lk,Bothongo ^[2] ; Sheena,Waters ^[2] ; Ruth,Dobson ^[2] ; Alastair J,Noyce ^[2] ; Kamaldeep S,Bhui ^[4] ; Ania,Korszun ^[3] ; Charles R,Marshall ^[2]

作者单位： Centre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, London, UK; Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK; Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. Electronic address: isabelle.foote@colorado.edu. ^[1] Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK. ^[2] Centre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, London, UK. ^[3] Centre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, London, UK; Department of Psychiatry and Nuffield Department of Primary Care Health Sciences, Medical Sciences Division, University of Oxford, Oxford, UK; World Psychiatric Association Collaborating Centre, Oxford, UK. ^[4]

关键词 Alzheimer's disease Dementia Dementia prevention Risk factors Shared genetics genomic SEM

医学主题词阿尔茨海默病(Alzheimer Disease);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);基因组学(Genomics);人类(Humans)

DOI 10.1016/j.neurobiolaging.2022.02.016

PMID 35797766

发布时间 2025-05-30

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