Genetic Disruption of the γ-Glutamylcysteine Ligase in PDAC Cells Induces Ferroptosis-Independent Cell Death In Vitro without Affecting In Vivo Tumor Growth.

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第一作者： Boutaina,Daher

第一单位： Medical Biology Department, Centre Scientifique de Monaco (CSM), 98000 Monaco, Monaco.

作者： Boutaina,Daher ^[1] ; Willian,Meira ^[1] ; Jerome,Durivault ^[1] ; Celia,Gotorbe ^[1] ; Jacques,Pouyssegur ^[1] ; Milica,Vucetic ^[2]

作者单位： Medical Biology Department, Centre Scientifique de Monaco (CSM), 98000 Monaco, Monaco. ^[1] Centre A. Lacassagne, Institute for Research on Cancer & Aging (IRCAN), Université Côte d'Azur, CNRS, INSERM, 061000 Nice, France. ^[2]

关键词 GPx4 ferroptosis glutathine lipid hydroperoxides γ-glutamylcysteine ligase

DOI 10.3390/cancers14133154

PMID 35804926

发布时间 2022-07-16

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Cancers

2022年14卷13期

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Genetic Disruption of the γ-Glutamylcysteine Ligase in PDAC Cells Induces Ferroptosis-Independent Cell Death In Vitro without Affecting In Vivo Tumor Growth.

Cancers

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Cancers

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Genetic Disruption of the γ-Glutamylcysteine Ligase in PDAC Cells Induces Ferroptosis-Independent Cell Death In Vitro without Affecting In Vivo Tumor Growth.

Cancers

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Cancers

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