Biophysical interaction between lanthanum chloride and (CG)<sub>n</sub> or (GC)<sub>n</sub> repeats: A reversible B-to-Z DNA transition.

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作者： Madhabi M,Bhanjadeo ^[1] ; Partha S,Nial ^[1] ; Chakkarai,Sathyaseelan ^[2] ; Ajit K,Singh ^[3] ; Juhi,Dutta ^[4] ; Thenmalarchelvi,Rathinavelan ^[2] ; Umakanta,Subudhi ^[5]

作者单位： DNA Nanotechnology & Application Laboratory, CSIR-Institute of Minerals & Materials Technology, Bhubaneswar 751 013, India; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad 201002, Uttar Pradesh, India. ^[1] Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi Campus, Telangana 502285, India. ^[2] Structural Biology Laboratory, DBT-Institute of Life Sciences, Bhubaneswar 751023, India; Department of Pharmacology, University of Vermont College of Medicine, Burlington 05405, USA. ^[3] School of Chemical Sciences, National Institute of Science Education & Research, Bhubaneswar 752050, India; Homi Bhaba National Institute, Mumbai 400094, India. ^[4] DNA Nanotechnology & Application Laboratory, CSIR-Institute of Minerals & Materials Technology, Bhubaneswar 751 013, India; Academy of Scientific & Innovative Research (AcSIR), Ghaziabad 201002, Uttar Pradesh, India. Electronic address: usubudhi@immt.res.in. ^[5]

关键词 B-Z transition CG repeat GC repeat Lanthanum Molecular dynamics simulation Z-DNA

主题词 DNA(DNA);DNA, Z型(DNA, Z-Form);依地酸(Edetic Acid);镧(Lanthanum);核酸构象(Nucleic Acid Conformation);寡核苷酸类(Oligonucleotides)

DOI 10.1016/j.ijbiomac.2022.07.020

PMID 35809677

发布时间 2022-08-17

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