Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma.

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作者： Beth E,Grace ^[1] ; Coralie M,Backlund ^[2] ; Duncan M,Morgan ^[1] ; Byong H,Kang ^[2] ; Nishant K,Singh ^[2] ; Brooke D,Huisman ^[3] ; C Garrett,Rappazzo ^[1] ; Kelly D,Moynihan ^[2] ; Laura,Maiorino ^[1] ; Connor S,Dobson ^[2] ; Taeyoon,Kyung ^[4] ; Khloe S,Gordon ^[1] ; Patrick V,Holec ^[2] ; Overbeck C Takou,Mbah ^[1] ; Daniel,Garafola ^[2] ; Shengwei,Wu ^[1] ; J Christopher,Love ^[2] ; K Dane,Wittrup ^[1] ; Darrell J,Irvine ^[2] ; Michael E,Birnbaum ^[1]

作者单位： Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States. ^[1] Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States. ^[2] Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States. ^[3] Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, United States. ^[4]

关键词 T cell receptor antigen endogenous retrovirus melanoma mimotope

主题词动物(Animals);抗原, 肿瘤(Antigens, Neoplasm);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);交叉反应(Cross Reactions);免疫疗法(Immunotherapy);黑色素瘤(Melanoma);小鼠(Mice)

DOI 10.3389/fimmu.2022.886683

PMID 35812387

发布时间 2022-11-12

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