Early loss of locus coeruleus innervation promotes cognitive and neuropathological changes before amyloid plaque deposition in a transgenic rat model of Alzheimer's disease.
第一作者:
Lisi,Flores-Aguilar
第一单位:
Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada.
作者:
主题词
阿尔茨海默病(Alzheimer Disease);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);淀粉样变性(Amyloidosis);动物(Animals);胆碱能药(Cholinergic Agents);认知(Cognition);疾病模型, 动物(Disease Models, Animal);蓝斑(Locus Coeruleus);神经生长因子类(Nerve Growth Factors);去甲肾上腺素(Norepinephrine);斑块, 淀粉样(Plaque, Amyloid);大鼠(Rats);大鼠, 转基因(Rats, Transgenic)
DOI
10.1111/nan.12835
PMID
35822518
发布时间
2022-09-14
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