Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries.
作者:
A Rouf,Banday [1]
;
Megan L,Stanifer [2]
;
Oscar,Florez-Vargas [1]
;
Olusegun O,Onabajo [1]
;
Brenen W,Papenberg [1]
;
Muhammad A,Zahoor [3]
;
Lisa,Mirabello [4]
;
Timothy J,Ring [1]
;
Chia-Han,Lee [1]
;
Paul S,Albert [5]
;
Evangelos,Andreakos [6]
;
Evgeny,Arons [7]
;
Greg,Barsh [8]
;
Leslie G,Biesecker [9]
;
David L,Boyle [10]
;
Mark S,Brahier [11]
;
Andrea,Burnett-Hartman [12]
;
Mary,Carrington [13]
;
Euijin,Chang [14]
;
Pyoeng Gyun,Choe [14]
;
Rex L,Chisholm [15]
;
Leandro M,Colli [16]
;
Clifton L,Dalgard [17]
;
Carolynn M,Dude [18]
;
Jeff,Edberg [19]
;
Nathan,Erdmann [20]
;
Heather S,Feigelson [12]
;
Benedito A,Fonseca [21]
;
Gary S,Firestein [10]
;
Adam J,Gehring [22]
;
Cuncai,Guo [23]
;
Michelle,Ho [1]
;
Steven,Holland [24]
;
Amy A,Hutchinson [25]
;
Hogune,Im [26]
;
Les'Shon,Irby [18]
;
Michael G,Ison [27]
;
Naima T,Joseph [28]
;
Hong Bin,Kim [29]
;
Robert J,Kreitman [7]
;
Bruce R,Korf [30]
;
Steven M,Lipkin [31]
;
Siham M,Mahgoub [32]
;
Iman,Mohammed [33]
;
Guilherme L,Paschoalini [16]
;
Jennifer A,Pacheco [15]
;
Michael J,Peluso [34]
;
Daniel J,Rader [35]
;
David T,Redden [36]
;
Marylyn D,Ritchie [35]
;
Brooke,Rosenblum [9]
;
M Elizabeth,Ross [33]
;
Hanaisa P Sant,Anna [37]
;
Sharon A,Savage [4]
;
Sudha,Sharma [38]
;
Eleni,Siouti [6]
;
Alicia K,Smith [18]
;
Vasiliki,Triantafyllia [6]
;
Joselin M,Vargas [1]
;
Jose D,Vargas [39]
;
Anurag,Verma [35]
;
Vibha,Vij [40]
;
Duane R,Wesemann [41]
;
Meredith,Yeager [25]
;
Xu,Yu [42]
;
Yu,Zhang [24]
;
Steeve,Boulant [43]
;
Stephen J,Chanock [37]
;
Jordan J,Feld [22]
;
Ludmila,Prokunina-Olsson [44]
作者单位:
Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
[1]
Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.;Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, USA.
[2]
Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
[3]
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
[4]
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
[5]
Laboratory of Immunobiology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
[6]
Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
[7]
HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA.
[8]
Center for Precision Health Research, National Human Genome Research Institute, Bethesda, MD, USA.
[9]
Altman Clinical & Translational Research Institute, UC San Diego Health Sciences, San Diego, CA, USA.
[10]
Georgetown University School of Medicine, Washington, DC, USA.
[11]
Institute for Health Research, Kaiser Permanente Colorado, Aurora, CO, USA.
[12]
Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.;Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.;Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
[13]
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
[14]
Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
[15]
Department of Medical Imaging, Hematology, and Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
[16]
Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
[17]
Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
[18]
Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.
[19]
Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
[20]
Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
[21]
Toronto Centre for Liver Disease, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.;Department of Immunology, University of Toronto, Toronto, Ontario, Canada.
[22]
Division of Cellular Polarity and Viral Infection, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[23]
Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
[24]
Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
[25]
Genome Opinion, Inc., Seoul, Republic of Korea.
[26]
Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
[27]
Department of Obstetrics & Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
[28]
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.;Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
[29]
Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.
[30]
Department of Medicine and Program in Mendelian Genetics, Weill Cornell Medicine, New York, NY, USA.
[31]
Department of Medicine, Infectious Diseases Division, Howard University Hospital, Howard University College of Medicine, Washington, DC, USA.
[32]
Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, USA.
[33]
Division of HIV, Infectious Diseases and Global Medicine, University of California, San Francisco, CA, USA.
[34]
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
[35]
Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA.
[36]
Laboratory of Genetic Susceptibility, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
[37]
Department of Biochemistry and Molecular Biology, National Human Genome Center, Howard University College of Medicine, Washington, DC, USA.
[38]
Veterans Affairs Medical Center, Washington, DC, USA.
[39]
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
[40]
Department of Medicine, Division of Allergy and Immunology, Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
[41]
Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
[42]
Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, Gainesville, FL, USA.;Division of Cellular Polarity and Viral Infection, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.
[43]
Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. prokuninal@mail.nih.gov.
[44]
DOI
10.1038/s41588-022-01113-z
PMID
35835913
发布时间
2024-09-23
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Nature genetics
Nature genetics
1103-1116页
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