SGLT2 inhibitor dapagliflozin reduces endothelial dysfunction and microvascular damage during cardiac ischemia/reperfusion injury through normalizing the XO-SERCA2-CaMKII-coffilin pathways.
作者:
主题词
肌动蛋白解聚因子类(Actin Depolymerizing Factors);动物(Animals);二苯甲基化合物(Benzhydryl Compounds);钙(Calcium);钙-钙调素依赖性蛋白激酶2型(Calcium-Calmodulin-Dependent Protein Kinase Type 2);内皮细胞(Endothelial Cells);葡糖苷类(Glucosides);人类(Humans);缺血(Ischemia);小鼠(Mice);心肌再灌注损伤(Myocardial Reperfusion Injury);黄嘌呤氧化酶(Xanthine Oxidase)
DOI
10.7150/thno.75121
PMID
35836807
发布时间
2023-01-11
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Theranostics
5034-5050页
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