Creatine riboside is a cancer cell-derived metabolite associated with arginine auxotrophy.

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第一作者： Amelia L,Parker

第一单位： Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA.

作者： Amelia L,Parker ^[1] ; Leila,Toulabi ^[1] ; Takahiro,Oike ^[1] ; Yasuyuki,Kanke ^[1] ; Daxeshkumar,Patel ^[1] ; Takeshi,Tada ^[1] ; Sheryse,Taylor ^[1] ; Jessica A,Beck ^[1] ; Elise,Bowman ^[1] ; Michelle L,Reyzer ^[2] ; Donna,Butcher ^[3] ; Skyler,Kuhn ^[4] ; Gary T,Pauly ^[5] ; Kristopher W,Krausz ^[6] ; Frank J,Gonzalez ^[6] ; S Perwez,Hussain ^[1] ; Stefan,Ambs ^[1] ; Bríd M,Ryan ^[1] ; Xin Wei,Wang ^[1] ; Curtis C,Harris ^[7]

作者单位： Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA. ^[1] National Research Resource for Imaging Mass Spectrometry, Vanderbilt University, Nashville, Tennessee, USA. ^[2] Pathology and Histotechnology Laboratory, Frederick National Laboratory, Frederick, Maryland, USA. ^[3] Center for Cancer Research Collaborative Bioinformatics Resource. ^[4] Chemical Biology Laboratory. ^[5] Laboratory of Metabolism, and. ^[6] Liver Cancer Program, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, USA. ^[7]

关键词 Cancer Lung cancer Oncology

主题词精氨酸(Arginine);肌酸(Creatine);人类(Humans);肝肿瘤(Liver Neoplasms);核糖核苷类(Ribonucleosides)

DOI 10.1172/JCI157410

PMID 35838048

发布时间 2022-09-23

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