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Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder.

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作者单位: Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. [1] Department of Psychiatry, Hanyang University Guri Hospital, Guri, 11923, Republic of Korea. [2] Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. [3] Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Republic of Korea. [4] Center for Supercomputing Applications, Division of National Supercomputing, Korea Institute of Science and Technology Information, Daejeon, 34141, Republic of Korea. [5] Department of Genetics, Yale Stem Cell Center, Yale Child Study Center, Yale School of Medicine, New Haven, CT, 06520, USA. [6] Center for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, 34141, Republic of Korea. [7] Industry-University Cooperation Foundation, Hanyang University, Seoul, 04763, Republic of Korea. [8] Department of Integrated Biomedical and Life Science, Korea University, Seoul, 02841, Republic of Korea. [9] BK21FOUR R&E Center for Learning Health Systems, Korea University, Seoul, 02841, Republic of Korea. [10] School of Biosystem and Biomedical Science, College of Health Science, Korea University, Seoul, 02841, Republic of Korea. [11] Department of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, 05030, Republic of Korea. [12] Department of Pharmacology, Eulji University, Daejeon, 13135, Republic of Korea. [13] Department of Psychiatry, Kyung Hee University Hospital, Seoul, 02447, Republic of Korea. [14] School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, 529020, China. [15] Organoid sciences, Ltd., Bundang-gu, Seongnam, 13488, Republic of Korea. [16] Center for Synaptic Brain Dysfunctions, Institute for Basic Science, Daejeon, 34141, Republic of Korea. eunjoonkim1@gmail.com. [17] Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. eunjoonkim1@gmail.com. [18] Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. jungkyoon@kaist.ac.kr. [19] Department of Psychiatry, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea. hjyoo@snu.ac.kr. [20] Department of Psychiatry, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea. hjyoo@snu.ac.kr. [21] Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea. jhlee4246@kaist.ac.kr. [22] Sovargen Co. Ltd., Daejeon, 34051, Republic of Korea. jhlee4246@kaist.ac.kr. [23]
DOI 10.1038/s41380-022-01697-2
PMID 35840799
发布时间 2023-04-07
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