Microwave synthesis and antimalarial screening of novel 4-amino benzoic acid (PABA)-substituted pyrimidine derivatives as <i>Plasmodium falciparum</i> dihydrofolate reductase inhibitors.

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作者： Ayesha Aktar Khanam,Choudhury ^[1] ; Sathishkumar,Vinayagam ^[2] ; Nayana,Adhikari ^[1] ; Surajit Kumar,Ghosh ^[1] ; Kamaraj,Sattu ^[2]

作者单位： Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, 786004 Assam India. ^[1] Department of Biotechnology, PG Extension Centre, Periyar University, Dharmapuri, 636701 Tamil Nadu India. ^[2]

关键词 Antimalarial activity Microwave organic synthesis Pf-DHFR Plasmodium falciparum Pyrimidine p-Aminobenzoic acid

DOI 10.1007/s13205-022-03236-w

PMID 35845109

发布时间 2023-08-02

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3 Biotech

2022年12卷8期

170页

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Microwave synthesis and antimalarial screening of novel 4-amino benzoic acid (PABA)-substituted pyrimidine derivatives as <i>Plasmodium falciparum</i> dihydrofolate reductase inhibitors.

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Microwave synthesis and antimalarial screening of novel 4-amino benzoic acid (PABA)-substituted pyrimidine derivatives as <i>Plasmodium falciparum</i> dihydrofolate reductase inhibitors.

3 Biotech

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3 Biotech

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