Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop <i>via</i> NRF2 in cancer therapeutic resistance.

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作者： Hong,Wang ^[1] ; Qianqian,Wang ^[1] ; Guodi,Cai ^[1] ; Zhijian,Duan ^[2] ; Zoann,Nugent ^[3] ; Jie,Huang ^[4] ; Jianwei,Zheng ^[1] ; Alexander D,Borowsky ^[5] ; Jian Jian,Li ^[6] ; Peiqing,Liu ^[1] ; Hsing-Jien,Kung ^[7] ; Leigh,Murphy ^[2] ; Hong-Wu,Chen ^[8] ; Junjian,Wang ^[3]

作者单位： School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. ^[1] Department of Biochemistry and Molecular Medicine, University of California, Davis, Sacramento, CA 95817, USA. ^[2] Research Institute in Oncology and Hematology, University of Manitoba and CancerCare Manitoba, Winnipeg R3E 0V9, Canada. ^[3] Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou 510080, China. ^[4] Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA 95817, USA. ^[5] Department of Radiation Oncology, University of California, Davis, Sacramento, CA 95817, USA. ^[6] National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou 510006, China. ^[7] UC Davis Comprehensive Cancer Center, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA. ^[8]

DOI 10.1016/j.apsb.2021.10.015

PMID 35847493

发布时间 2022-07-19

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Acta pharmaceutica Sinica. B

2022年12卷4期

1871-1884页

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Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop <i>via</i> NRF2 in cancer therapeutic resistance.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

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Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop <i>via</i> NRF2 in cancer therapeutic resistance.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

相关期刊

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