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AFM13 in patients with relapsed or refractory classical Hodgkin lymphoma: final results of an open-label, randomized, multicenter phase II trial.

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第一作者： Stephanie,Sasse

第一单位： German Hodgkin Study Group (GHSG), Cologne, Germany.;Clinic for Hematology, Oncology and Gastroenterology, Maria Hilf Hospital Moenchengladbach, Moenchengladbach, Germany.

作者： Stephanie,Sasse ^[1] ; Paul Jan,Bröckelmann ^[2] ; Jesko,Momotow ^[2] ; Annette,Plütschow ^[2] ; Andreas,Hüttmann ^[3] ; Nadezda,Basara ^[4] ; Christian,Koenecke ^[5] ; Sonja,Martin ^[6] ; Martin,Bentz ^[7] ; Christina,Grosse-Thie ^[8] ; Sven,Thorspecken ^[9] ; Maike,de Wit ^[10] ; Carsten,Kobe ^[11] ; Markus,Dietlein ^[11] ; Bastian von,Tresckow ^[12] ; Michael,Fuchs ^[2] ; Peter,Borchmann ^[2] ; Andreas,Engert ^[2]

作者单位： German Hodgkin Study Group (GHSG), Cologne, Germany.;Clinic for Hematology, Oncology and Gastroenterology, Maria Hilf Hospital Moenchengladbach, Moenchengladbach, Germany. ^[1] German Hodgkin Study Group (GHSG), Cologne, Germany.;Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), University of Cologne, Cologne, Germany. ^[2] Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[3] St. Franziskus Hospital Flensburg, Flensburg, Germany. ^[4] Department of Hematology, Hemostaseology, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany. ^[5] Department of Hematology, Oncology, Palliative Medicine, Robert-Bosch-Hospital, Stuttgart, Germany. ^[6] Municipal Hospital Karlsruhe, Karlsruhe, Germany. ^[7] Department of Internal Medicine, Medical Clinic III - Hematology, Oncology, Palliative Medicine, Rostock University Medical Center, Rostock, Germany. ^[8] Hematology, Oncology, Immunology, Hospital Schwabing, München, Germany. ^[9] Department of Medicine - Hematology, Oncology, Palliative Medicine, Vivantes Hospital Neukölln, Berlin, Germany. ^[10] German Hodgkin Study Group (GHSG), Cologne, Germany.;Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany. ^[11] German Hodgkin Study Group (GHSG), Cologne, Germany.;Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[12]

关键词 AFM13 NK-cell mediated immune-response Relapsed classical Hodgkin lymphoma bispecific anti-CD30/CD16A-antibody immunotherapy phase II trial

医学主题词抗体, 单克隆(Antibodies, Monoclonal);抗肿瘤药(Antineoplastic Agents);霍奇金病(Hodgkin Disease);人类(Humans);免疫轭合物(Immunoconjugates);肿瘤复发, 局部(Neoplasm Recurrence, Local)

DOI 10.1080/10428194.2022.2095623

PMID 35848865

发布时间 2025-10-31

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