Kaiso phosphorylation at threonine 606 leads to its accumulation in the cytoplasm, reducing its transcriptional repression of the tumour suppressor CDH1.

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第一作者： Wei,Tian

第一单位： Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Cancer Etiology, Peking University Cancer Hospital and Institute, Beijing, China.

作者： Wei,Tian ^[1] ; Hongfan,Yuan ^[1] ; Sisi,Qin ^[1] ; Wensu,Liu ^[1] ; Baozhen,Zhang ^[1] ; Liankun,Gu ^[1] ; Jing,Zhou ^[1] ; Dajun,Deng ^[1]

作者单位： Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Division of Cancer Etiology, Peking University Cancer Hospital and Institute, Beijing, China. ^[1]

关键词 14-3-3 proteins AKT1 Kaiso P120ctn cancer phosphorylation transcription factor

主题词抗原, CD(Antigens, CD);钙黏着糖蛋白类(Cadherins);细胞质(Cytoplasm);人类(Humans);磷酰化(Phosphorylation);苏氨酸(Threonine);转录因子(Transcription Factors)

DOI 10.1002/1878-0261.13292

PMID 35851744

发布时间 2022-09-16

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