Targeting the deubiquitinase USP7 for degradation with PROTACs.

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第一作者： Arunima,Murgai

第一单位： Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. jan.kroenke@charite.de.

作者： Arunima,Murgai ^[1] ; Izidor,Sosič ^[2] ; Martina,Gobec ^[3] ; Patricia,Lemnitzer ^[3] ; Matic,Proj ^[1] ; Sophie,Wittenburg ^[3] ; Rabea,Voget ^[4] ; Michael,Gütschow ^[4] ; Jan,Krönke ^[4] ; Christian,Steinebach ^[1]

作者单位： Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. jan.kroenke@charite.de. ^[1] German Cancer Consortium (DKTK) partner site Berlin and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[2] Faculty of Pharmacy, University of Ljubljana, SI-1000, Ljubljana, Slovenia. ^[3] Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany. c.steinebach@uni-bonn.de. ^[4]

主题词细胞凋亡(Apoptosis);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);肿瘤(Neoplasms)

DOI 10.1039/d2cc02094g

PMID 35852517

发布时间 2023-08-05

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准确一般字义偏差语意偏离译文作用小提交