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Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.

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第一作者: Daniel,Bottomly
第一单位: Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.
作者: Daniel,Bottomly [1] ; Nicola,Long [2] ; Anna Reister,Schultz [3] ; Stephen E,Kurtz [2] ; Cristina E,Tognon [2] ; Kara,Johnson [2] ; Melissa,Abel [3] ; Anupriya,Agarwal [4] ; Sammantha,Avaylon [2] ; Erik,Benton [5] ; Aurora,Blucher [1] ; Uma,Borate [6] ; Theodore P,Braun [2] ; Jordana,Brown [3] ; Jade,Bryant [3] ; Russell,Burke [2] ; Amy,Carlos [7] ; Bill H,Chang [8] ; Hyun Jun,Cho [9] ; Stephen,Christy [2] ; Cody,Coblentz [2] ; Aaron M,Cohen [10] ; Amanda,d'Almeida [3] ; Rachel,Cook [2] ; Alexey,Danilov [11] ; Kim-Hien T,Dao [12] ; Michie,Degnin [2] ; James,Dibb [2] ; Christopher A,Eide [2] ; Isabel,English [2] ; Stuart,Hagler [5] ; Heath,Harrelson [5] ; Rachel,Henson [7] ; Hibery,Ho [2] ; Sunil K,Joshi [2] ; Brian,Junio [2] ; Andy,Kaempf [13] ; Yoko,Kosaka [9] ; Ted,Laderas [14] ; Matt,Lawhead [5] ; Hyunjung,Lee [3] ; Jessica T,Leonard [2] ; Chenwei,Lin [7] ; Evan F,Lind [9] ; Selina Qiuying,Liu [2] ; Pierrette,Lo [2] ; Marc M,Loriaux [15] ; Samuel,Luty [2] ; Julia E,Maxson [16] ; Tara,Macey [2] ; Jacqueline,Martinez [2] ; Jessica,Minnier [17] ; Andrea,Monteblanco [2] ; Motomi,Mori [18] ; Quinlan,Morrow [3] ; Dylan,Nelson [19] ; Justin,Ramsdill [5] ; Angela,Rofelty [3] ; Alexandra,Rogers [2] ; Kyle A,Romine [3] ; Peter,Ryabinin [1] ; Jennifer N,Saultz [2] ; David A,Sampson [2] ; Samantha L,Savage [2] ; Robert,Schuff [20] ; Robert,Searles [7] ; Rebecca L,Smith [2] ; Stephen E,Spurgeon [2] ; Tyler,Sweeney [2] ; Ronan T,Swords [2] ; Aashis,Thapa [2] ; Karina,Thiel-Klare [2] ; Elie,Traer [2] ; Jake,Wagner [2] ; Beth,Wilmot [5] ; Joelle,Wolf [2] ; Guanming,Wu [10] ; Amy,Yates [5] ; Haijiao,Zhang [16] ; Christopher R,Cogle [21] ; Robert H,Collins [22] ; Michael W,Deininger [23] ; Christopher S,Hourigan [24] ; Craig T,Jordan [25] ; Tara L,Lin [26] ; Micaela E,Martinez [27] ; Rachel R,Pallapati [27] ; Daniel A,Pollyea [25] ; Anthony D,Pomicter [28] ; Justin M,Watts [29] ; Scott J,Weir [30] ; Brian J,Druker [31] ; Shannon K,McWeeney [32] ; Jeffrey W,Tyner [33]
作者单位: Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA. [1] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Division of Hematology & Medical Oncology, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA. [2] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA. [3] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR 97239, USA; Division of Oncologic Sciences, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA. [4] Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR 97239, USA. [5] Division of Hematology, Department of Internal Medicine, James Cancer Center, Ohio State University, Columbus, OH 43210, USA. [6] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Integrated Genomics Laboratory, Oregon Health & Science University, Portland, OR 97239, USA. [7] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Division of Hematology and Oncology, Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA. [8] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA. [9] Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR 97239, USA. [10] Department of Hematology and Hematopoietic Stem Cell Transplant, City of Hope National Medical Center, Duarte, CA 91010, USA. [11] Astex Pharmaceuticals, Cambridge, CB4 0QA, UK. [12] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Biostatistics Shared Resource, Oregon Health & Science University, Portland, OR 97239, USA. [13] DNA Nexus, Mountain View, CA 94040, USA. [14] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Department of Pathology, Oregon Health & Science University, Portland, OR 97239, USA. [15] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Division of Oncologic Sciences, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA. [16] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Biostatistics Shared Resource, Oregon Health & Science University, Portland, OR 97239, USA; OHSU-PSU School of Public Health, VA Portland Health Care System, Oregon Health & Science University, Portland, OR 97239, USA. [17] Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. [18] High-Throughput Screening Services Laboratory, Oregon State University, Corvallis, OR 97331, USA. [19] Ochin Inc., Portland, OR 97228, USA. [20] Department of Medicine, Division of Hematology and Oncology, University of Florida, Gainesville, FL 32610, USA. [21] Department of Internal Medicine/ Hematology Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8565, USA. [22] Division of Hematology & Hematologic Malignancies, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. [23] National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20814-1476, USA. [24] Division of Hematology, University of Colorado, Denver, CO 80045, USA. [25] Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas, Kansas City, KS 66205, USA. [26] Clinical Research Services, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA. [27] Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. [28] Division of Hematology, Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA. [29] Department of Cancer Biology, Division of Medical Oncology, Department of Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA. [30] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Division of Hematology & Medical Oncology, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: drukerb@ohsu.edu. [31] Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA; Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: mcweeney@ohsu.edu. [32] Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA; Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: tynerj@ohsu.edu. [33]
DOI 10.1016/j.ccell.2022.07.002
PMID 35868306
发布时间 2026-05-28
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