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Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis.

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第一作者： Moritz,Oster

第一单位： Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Pharmacology, Cardiovascular Metabolic Renal (CMR)-Research Center, Berlin, Germany.

作者： Moritz,Oster ^[1] ; Markus,Galhuber ^[2] ; Jelena,Krstic ^[2] ; Julia S,Steinhoff ^[1] ; Georgia,Lenihan-Geels ^[3] ; Sascha,Wulff ^[1] ; Marie F,Kiefer ^[1] ; Konstantin M,Petricek ^[1] ; Sylvia J,Wowro ^[1] ; Roberto E,Flores ^[1] ; Na,Yang ^[1] ; Chen,Li ^[1] ; Yueming,Meng ^[1] ; Isabel,Reinisch ^[2] ; Manuela,Sommerfeld ^[1] ; Stefan,Weger ^[4] ; Hansjörg,Habisch ^[5] ; Tobias,Madl ^[5] ; Tim J,Schulz ^[6] ; Andreas,Prokesch ^[2] ; Michael,Schupp ^[7]

作者单位： Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Pharmacology, Cardiovascular Metabolic Renal (CMR)-Research Center, Berlin, Germany. ^[1] Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Medical University of Graz, Graz, Austria. ^[2] Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition, Nuthetal, Germany. ^[3] Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Virology, Campus Benjamin Franklin, Berlin, Germany. ^[4] Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria. ^[5] Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition, Nuthetal, Germany; German Center for Diabetes Research (DZD), München-Neuherberg, Germany; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany. ^[6] Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Pharmacology, Cardiovascular Metabolic Renal (CMR)-Research Center, Berlin, Germany. Electronic address: michael.schupp@charite.de. ^[7]

关键词 Foxo1 fasting glucose metabolism glycogen liver p53 triglycerides