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Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults.

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作者单位: Department of Neurosurgery, Medical School, University of Pecs, 2 Ret Street, Pecs, 7624, Hungary. [1] Institute for Translational Medicine, Medical School, University of Pecs, Pecs, Hungary. [2] Vascular Cognitive Impairment and Neurodegeneration Program, Oklahoma Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. [3] ELKH-PTE Clinical Neuroscience MR Research Group, Eötvös Lóránd Research Network (ELKH), Pecs, Hungary. [4] Department of Neurology, Medical School, University of Pecs, Pecs, Hungary. [5] Department of Health Promotion Sciences, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. [6] The Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA. [7] International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine/Department of Public Health, Semmelweis University, Budapest, Hungary. [8] Department of Neurosurgery, Medical School, University of Pecs, 2 Ret Street, Pecs, 7624, Hungary. toth.peter@pte.hu. [9] Institute for Translational Medicine, Medical School, University of Pecs, Pecs, Hungary. toth.peter@pte.hu. [10] Vascular Cognitive Impairment and Neurodegeneration Program, Oklahoma Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. toth.peter@pte.hu. [11] International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine/Department of Public Health, Semmelweis University, Budapest, Hungary. toth.peter@pte.hu. [12]
DOI 10.1007/s11357-022-00623-2
PMID 35869380
发布时间 2023-11-06
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