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Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.

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第一作者： Anton N,Shuvaev

第一单位： Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.

作者： Anton N,Shuvaev ^[1] ; Olga S,Belozor ^[1] ; Oleg I,Mozhei ^[2] ; Andrey N,Shuvaev ^[3] ; Yana V,Fritsler ^[3] ; Elena D,Khilazheva ^[1] ; Angelina I,Mosyagina ^[1] ; Hirokazu,Hirai ^[4] ; Anja G,Teschemacher ^[5] ; Sergey,Kasparov ^[6]

作者单位： Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia. ^[1] Institute of Living Systems, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia. ^[2] Institute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia. ^[3] Department of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan. ^[4] Department of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol BS8 1TH, UK. ^[5] Institute of Living Systems, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia.;Department of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol BS8 1TH, UK. ^[6]

关键词 Bergmann glia DSE LTD PPD PPF Purkinje cells spinocerebellar ataxia type 1 synaptic plasticity

医学主题词动物(Animals);疾病模型, 动物(Disease Models, Animal);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);神经元可塑性(Neuronal Plasticity);浦肯野细胞(Purkinje Cells);脊髓小脑共济失调(Spinocerebellar Ataxias)

DOI 10.3390/cells11142247

PMID 35883691

发布时间 2025-10-31

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