首页> Brain communications> 4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in <i>SLC6A1</i> patient variant-bearing cell and mouse models.

4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in <i>SLC6A1</i> patient variant-bearing cell and mouse models.

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第一作者： Gerald,Nwosu

第一单位： Department of Neurology, Vanderbilt University Medical Center, 465 21st Ave South, Nashville, TN 37232, USA.

作者： Gerald,Nwosu ^[1] ; Felicia,Mermer ^[1] ; Carson,Flamm ^[2] ; Sarah,Poliquin ^[1] ; Wangzhen,Shen ^[1] ; Kathryn,Rigsby ^[2] ; Jing Qiong,Kang ^[1]

作者单位： Department of Neurology, Vanderbilt University Medical Center, 465 21st Ave South, Nashville, TN 37232, USA. ^[1] Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA. ^[2]

关键词 4-phenylbutyrate acid GABA transporter 1 (GAT-1)autism chaperone epilepsy

DOI 10.1093/braincomms/fcac144

PMID 35911425

发布时间 2023-02-12

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4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in <i>SLC6A1</i> patient variant-bearing cell and mouse models.

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4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in <i>SLC6A1</i> patient variant-bearing cell and mouse models.

Brain communications

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Brain communications

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